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Is Namzaric the same as Namenda? The FDA has now approved a combination pill for people with moderate to severe Alzheimer's disease. The pill is called Namzaric and combines memantine hydrochloride extended-release (also known as Namenda) and donepezil hydrocholoride (also known as Aricept). Currently 70% of people on Namenda XR are also on Aricept.
How does memantine hydrochloride work? Glutamate can damage the nerve cells by excessively stimulating the NMDA receptors. Memantine works by blocking the NMDA receptors in the brain. This blocks the excessive activity of glutamate, but still allows the normal activation of these receptors that occurs when the brain forms a memory.
Does memantine help dementia? Memantine helps to keep cells from being overstimulated or getting "burned out" from too much glutamate. Memantine is more commonly prescribed to individuals in middle to late stages of dementia since it can often help individuals for whom cholinesterase inhibitors have stopped working.
What does Namenda do to the brain? Memantine is used to treat moderate to severe confusion (dementia) related to Alzheimer's disease. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions.
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